Dustin Maly

Our group aims to understand and control the enzyme families involved in intracellular signal transduction. The final goal of these studies is to identify new molecular targets for the treatment of human disease. We integrate techniques from organic chemistry, biochemistry, protein engineering, proteomics, and cell biology to develop new tools that provide a greater understanding of diverse signaling processes. Our technological innovations seek to address the limitations of currently existing methods for studying these highly dynamic cellular events. Furthermore, we are using these tools to answer a number of fundamental questions in biology.